Medical dermatology

Vitiligo

Loss of skin pigment in patches — our dermatologists offer the latest treatments including Opzelura (ruxolitinib), phototherapy, and repigmentation therapy.

Types of Vitiligo

Nonsegmental (generalized): most common; symmetric patches that can spread over time
Segmental: unilateral, follows a dermatomal pattern, often stable; responds less to medical therapy but well to surgical grafting

Active vs. Stable Vitiligo

Active vitiligo spreads; stable vitiligo has not changed in 1–2 years. Stability is important for surgical candidacy.

Treatment Options

Medical

Ruxolitinib cream (Opzelura) — JAK1/JAK2 inhibitor; FDA-approved 2022; first-line for facial and body vitiligo in patients ≥ 12 years
Narrowband UVB phototherapy — highly effective; requires consistent sessions
Topical corticosteroids / calcineurin inhibitors — adjunct therapy for limited areas

Surgical

Suction blister grafting and punch grafting — for stable segmental or focal vitiligo
Melanocyte-keratinocyte transplantation — advanced option at select centers

Camouflage

Self-tanning products (DHA-based), medical cosmetic cover-up for quality-of-life support

Emotional & Psychological Impact

Vitiligo significantly impacts quality of life, especially in patients with darker skin tones. Holistic care including dermatology and mental health support is recommended.

Frequently asked questions

Is Opzelura (ruxolitinib) cream covered by insurance for vitiligo?

Coverage varies by plan. Opzelura received FDA approval for vitiligo in 2022 and many commercial insurers cover it with prior authorization. Our staff can assist with insurance appeals and patient assistance programs.

Can vitiligo spread to cover the whole body?

In some patients, vitiligo progresses to involve large body surface areas (universal vitiligo). However, progression is unpredictable — some patients stabilize with minimal spread, especially with treatment.

Most insurance plans cover medical dermatology procedures. Contact us to verify your benefits.

Trusted sources

This page is educational. Specific treatment decisions are made during your visit with Dr. Puyana.

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Treatment Options

Medical

Ruxolitinib cream (Opzelura) — JAK1/JAK2 inhibitor; FDA-approved 2022; first-line for facial and body vitiligo in patients ≥ 12 years

Narrowband UVB phototherapy — highly effective; requires consistent sessions

Topical corticosteroids / calcineurin inhibitors — adjunct therapy for limited areas

Surgical

Suction blister grafting and punch grafting — for stable segmental or focal vitiligo

Melanocyte-keratinocyte transplantation — advanced option at select centers

Camouflage

Self-tanning products (DHA-based), medical cosmetic cover-up for quality-of-life support

Frequently asked questions

Is Opzelura (ruxolitinib) cream covered by insurance for vitiligo?

Can vitiligo spread to cover the whole body?

Book a consultation

Tell us a little about what you need. Our team responds in the language you choose.